Chantix / Varenicline - Overview

    Varenicline, formerly marketed under the brand Chantix, is a prescription medication used as an aid smoking cessation. The brand-name Chantix product has been discontinued in the United States and generic varenicline is the form most commonly prescribed and dispensed. People who want help quitting smoking can connect with a licensed medical provider through Push Health who can prescribe varenicline (including starter packs) when appropriate to do so.

    How Does Chantix (Varenicline) Work?

    Varenicline tartrate is used as an aid to smoking cessation and belongs to a class of nicotinic receptor partial agonists. The medication binds to α4β2 nicotinic acetylcholine receptors in the brain and reduces the rewarding effects of nicotine and helps ease withdrawal. Blocking nicotine activation of these receptors is thought to reduce the reward experienced upon smoking. It is considered more effective than bupropion (Zyban) or nicotine replacement therapy alone when used with behavioral support.

    It is FDA-approved as an aid to smoking cessation. There are anecdotal reports of Chantix medication being used to help people who want to quit using smokeless tobacco products like Zyn but it is are not currently approved by the FDA for that use. For more detailed information, see the varenicline page.

    Chantix (Varenicline) - Dosage and Cost

    Chantix (varenicline) medication is typically prescribed in standard dosing protocols (subject to the judgment of the medical provider):

    • Days 1-3: 0.5 mg once daily
    • Days 4-7: 0.5 mg twice daily
    • Day 8 onward: 1 mg twice daily

    Treatment usually continues for 12 weeks and an additional 12-week course may be offered to those who have successfully quit to help prevent relapse. A flexible "reduce-to-quit" approach is also an option for patients who are not ready to set an immediate quit date. It is recommended that patients take each dose with food and a full glass of water to help reduce nausea.

    Generic varenicline is substantially more affordable than the formerly branded Chantix. Many insurance plans and Medicaid programs cover tobacco-cessation medications with little or no cost-sharing. Savings cards and pharmacy coupons can further reduce out-of-pocket cost.

    Can I Buy Chantix / Varenicline Online?

    Chantix (varenicline) is a prescription medication and is not available over-the-counter. Through Push Health, patients can be connected with a licensed medical provider who can prescribe Chantix (varenicline) - including the starter pack followed by maintenance tablets - when appropriate to do so.

    Chantix (Varenicline) - Side Effects

    Chantix (varenicline) prescription tablets can cause side effects when used. The medication can also cause serious neuropsychiatric events, including but not limited to depression and suicidal ideation, behavior changes, hostility, and agitation. Dose adjustments may be needed in patients with kidney problems. Varenicline is not recommended for use in patients under 18 years of age. Anyone with an allergy or hypersensitivity to varenicline or ingredients in the formulation should also avoid using it. All questions regarding Chantix (varenicline) side effects should be directed to one's medical provider and pharmacist.

    How to Get a Chantix Prescription with Push Health

    1. Complete a brief health intake. Answer a few questions about your smoking history, current medications, and relevant medical history - including kidney disease or any psychiatric conditions.
    2. Connect with a licensed medical provider. A provider will review your information and evaluate whether varenicline is appropriate, including the best quit strategy and duration. Same-day consultations are available.
    3. Receive your prescription electronically. If approved, a varenicline prescription will be sent to the pharmacy of your choice - no office visit required.
    4. Begin your quit plan. Start the medication 1-2 weeks before your target quit date or follow a flexible reduction plan. Take it with food and water and follow up if you have side effects or questions.

    No health insurance or subscription is required. Medical providers are available now.

    More Chantix Information

    Last updated August 13, 2026. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions. Please call 911 immediately or go to the nearest emergency room if you believe you are experiencing a medical emergency.